PUMA BH3 is a p53 upregulated modulator of apoptosis (PUMA) BH3 domain peptide, acts as a direct activator of Bak, with a Kd of 26 nM.This is a PUMA BH3 domain peptide. PUMA proteins bind Bcl-2, localize to the mitochondria, and induce cytochrome C release and apoptosis in response to p53. PUMA may be a direct mediator of p53-induced apoptosis.

Glycocholic Acid Sodium Salt is a conjugated bile salt and ionic biologic detergent. It is involved in the emulsification of fats.

Caspase-3 inhibitor. Inhibits MG 132-induced small cell lung cancer cell death in vitro.